Recombinant Phospho-Raf-B (Thr401) Monoclonal Antibody

SKU: AN300708L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Raf-B

Target Synonym:RAFB;BRAF;B-RAF1;B-raf;BRAF1;NS7;RAFB1;serine/threonine-protein kinase B-raf;B-raf;BRAF1;B-RAF1;NS7;RAFB1;serine/threonine-protein kinase B-raf;94 kDa B raf protein;B raf 1;B Raf proto oncogene;B Raf proto oncogene serine threonine protein kinase;B RAF1;BRAF 1;B-Raf proto-oncogene serine/threonine-protein kinase (p94);cRmil;FLJ95109;MGC126806;MGC138284;Murine sarcoma viral (v-raf) oncogene homolog B1;Murine sarcoma viral v raf oncogene homolog B1;Oncogen BRAF;oncogene BRAF1;p94;proto-oncogene B-Raf;Proto-oncogene c-Rmil;RAFB 1;RMIL;serine/threonine kinase;v raf murine sarcoma viral oncogene homolog B;v raf murine sarcoma viral oncogene homolog B1;v-Raf murine sarcoma viral oncogene homolog B1

Research Areas:Cell Biology;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:12G3

UNIProt ID:P15056

Accession:

Background:This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Thr401) of Human Phospho-Raf-B

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:84 kDa

ObservedMW:84 kDa