Recombinant Phospho-IGF1R (Tyr1135/1136)/Phospho-Insulin Receptor β (Tyr1150/1151) Monoclonal Antibody

SKU: AN301299L

Size::

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:IGF1R

Target Synonym:HHF;CD220;HHF5;INSR;IR;Insulin R;INSR;IR;Insulin Receptor;IGF IR;Insulin Receptor β

Research Areas:Signal Transduction;Neuroscience;Cancer;Cardiovascular;Metabolism;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5C10

UNIProt ID:P06213;P08069

Accession:

Background:This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Tyr1135/1136)/(Tyr1150/1151) of Human Phospho-IGF1R/Phospho-Insulin Receptor β

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:156 kDa

ObservedMW:95 kDa