Recombinant Phospho-CaMKII α, β (Thr286) Monoclonal Antibody

SKU: AN301143L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:CaMKII α, β

Target Synonym:KIAA;CAMK2A;CAMKA;KIAA0968;Alpha CaMKII;Calcium calmodulin dependent protein kinase II;Calcium/calmodulin dependent protein kinase II alpha B subunit;Calcium/calmodulin dependent protein kinase type II alpha chain;Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha;Calcium/calmodulin-dependent protein kinase II alpha;Calcium/calmodulin-dependent protein kinase II-alpha;Calcium/calmodulin-dependent protein kinase type II subunit alpha;Calcium/calmodulin-dependent protein kinase type IIA;CaM kinase II alpha chain;CaM kinase II alpha subunit;CaM kinase II subunit alpha;CaMK II alpha subunit;CaMKII;CaMK-II subunit alpha;CaMKIINalpha;EC 2.7.11.17;KCC2A;MGC123320;MGC139375;MGC155201;mKIAA0968;PK2CDD;PKCCD;R74975;zgc:112538;zgc:123320;CaMKIIα/β

Research Areas:Neuroscience;Signal Transduction;Cardiovascular;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6H4

UNIProt ID:Q9UQM7;Q13554

Accession:

Background:The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Thr286) of Human Phospho-CaMKII α, β

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:54 kDa

ObservedMW:54 kDa