Recombinant PDK4 Monoclonal Antibody

SKU: AN302015L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:PDK4

Target Synonym:PDK;PDHK;Pyruvate dehydrogenase lipoamide kinase isozyme;PDK4 PDHK;PDK4;FLJ40832;mitochondrial;Pyruvate dehydrogenase lipoamide kinase isozyme 4;PDK4 PDHK4;PDHK4;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4;Pyruvate dehydrogenase [lipoamide] kinase isozyme 4 mitochondrial;Pyruvate dehydrogenase kinase 4;Pyruvate dehydrogenase kinase isoenzyme 4;Pyruvate dehydrogenase kinase isoform 4;Pyruvate dehydrogenase kinase isozyme 4;Pyruvate dehydrogenase kinase isozyme 4 mitochondrial

Research Areas:Signal Transduction;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Rat;Mouse

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A735

UNIProt ID:Q16654

Accession:

Background:Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis. Enhanced PDK4 expression may be caused by the increase in free fatty acids that occurs during starvation. Free fatty acids can activate peroxisome proliferator-activated receptor α (PPARα), and activation of PPARα can promote PDK4 expression.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000

Calculated MW:46 kDa

ObservedMW:44 kDa