Recombinant p38 Monoclonal Antibody

SKU: AN300925L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:p38

Target Synonym:Mxi;MAPK;CSPB;MAP kinase MXI;MAX-interacting protein;Mitogen-activated protein kinase;MAPK14;CSBP;CSBP1;CSBP2;CSPB1;EXIP;Mxi2;PRKM14;PRKM15;RK;SAPK2A;p38;p38ALPHA;p38 MAPK;MAP kinase MXI2;MAX-interacting protein 2;Mitogen-activated protein kinase 14;CSAID binding protein;CSAID Binding Protein 1;CSAID-binding protein;Csaids binding protein;CSBP 1;CSBP 2;Cytokine suppressive anti-inflammatory drug-binding protein;MAP kinase 14;MAP kinase p38 alpha;MAPK 14;MAX interacting protein 2;Mitogen Activated Protein Kinase 14;Mitogen activated protein kinase p38 alpha;Mitogen-activated protein kinase p38 alpha;MK14;Mxi 2;p38 ALPHA;p38 MAP kinase;p38 mitogen activated protein kinase;p38alpha Exip;p38-α

Research Areas:Signal Transduction;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:9A10

UNIProt ID:Q16539

Accession:

Background:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human p38 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000;IHC 1:50-1:300

Calculated MW:41 kDa

ObservedMW:41 kDa