Recombinant OLR1/LOX1 Monoclonal Antibody

SKU: AN301759L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:OLR1/LOX1

Target Synonym:OLR;Ox-LDL receptor;lectin-type oxidized LDL receptor;Oxidized low-density lipoprotein receptor;SLOX;SCARE;lectin-type oxidized LDL receptor 1;LOX-1;LOXIN;Oxidized low-density lipoprotein receptor 1;Ox-LDL receptor 1;SCARE1;SLOX1;CLEC8A;LOX1;OLR1;C-type lectin domain family 8 member A;hLOX 1;hLOX-1;Lectin like oxidized LDL receptor 1;Lectin like oxLDL receptor 1;Lectin type oxidized LDL receptor 1;Lectin-like oxidized LDL receptor 1;Lectin-like oxLDL receptor 1;low density lipoprotein oxidized;member 1;Ox LDL receptor 1;Oxidised low density lipoprotein (lectin like) receptor 1;Oxidized low density lipoprotein receptor 1;Oxidized low density lipoprotein receptor 1 soluble form;receptor 1;Scavenger receptor class E;soluble form;SR-EI

Research Areas:Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IF;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A467

UNIProt ID:P78380

Accession:

Background:This protein is a low density lipoprotein receptor that belongs to the C-type lectin superfamily. It is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. Diseases associated with OLR1 include Myocardial Infarction and Chlamydia Pneumonia. Among its related pathways are Innate Immune System and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and low-density lipoprotein particle receptor activity.

Concentration:1 mg/mL

Immunogen:Recombinant human OLR1/LOX1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:5000;IF 1:50;FCM 1:50-1:100

Calculated MW:31 kDa

ObservedMW:55 kDa