Recombinant Oct-4 Monoclonal Antibody

SKU: AN300895L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Oct-4

Target Synonym:POU5F;OTF;POU5F1;OTF-3;OTF3;OTF4;Oct-3;Oct-4;OCT-3/4;Octamer-4;POU Class 5 Homoeobox 1;POU Domain Class 5 Transcription Factor 1;POU5F1/OCT4

Research Areas:Epigenetics and Nuclear Signaling;Stem Cells;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:7C8

UNIProt ID:Q01860

Accession:

Background:This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation withThe Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One ofThe AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Oct-4 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:39 kDa

ObservedMW:45 kDa