Recombinant NFkB-p100 Monoclonal Antibody

SKU: AN300722L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:NFkB-p100

Target Synonym:CVID;H2TF;NFKB;NF-kB;p49/p;LYT;CVID10;H2TF1;LYT-10;LYT10;NF-kB2;p100;p49/p100;p52;NFKB2;p105;NF-κB p100/p52

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11A4

UNIProt ID:Q00653

Accession:

Background:NFKB2(nuclear factor kappa B subunit 2) Homo sapiens This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human NFkB-p100 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:97 kDa

ObservedMW:120 kDa