Recombinant Mouse Csf3 Protein(Trx Tag)

SKU: PDEM100115

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:Csf3

Target Synonym:CSF;TNFSF;C17orf;C17orf33;CD254;CSF3OS;Filgrastim;GCSF;G-CSF;Granulocyte colony-stimulating factor;Lenograstim;ODF (Osteoclast Differentiation Factor);OPGL;Pluripoietin;soluble Receptor Activator of NF-kB Ligand;sRNAK Ligand;TNFSF11;TRANCE (TNF-Related Activation-induced Cytokine);Csfg;Csf3

Research Areas:Immunology;Cancer;Cell Biology;Signal Transduction;Stem cells

Conjugation:

Target Species:Mouse

Expression Host:E.coli

Application:

Fusion tag:N-Trx

UNIProt ID:P09920

Accession:P09920

Background:Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent.

Concentration:

Activity:Not validated for activity

Sequence:Val31-Ala208

Purity:> 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method

Calculated MW:39.6 kDa

ObservedMW:35 kDa