Recombinant Mouse Ccl24 Protein(Trx Tag)

SKU: PDEM100130

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:Ccl24

Target Synonym:C-C motif chemokine 24;CCL24;CCL24;Chemokine CC Motif Ligand 24;CK beta 6;CK-beta-6;Ckb6;Eosinophil chemotactic protein 2;Eotaxin-2;MPIF-2;MPIF2;Myeloid progenitor inhibitory factor 2;SCYA24;Small inducible cytokine subfamily A (Cys-Cys) member 24;Small-inducible cytokine A24

Research Areas:Immunology

Conjugation:

Target Species:Mouse

Expression Host:E.coli

Application:

Fusion tag:N-Trx

UNIProt ID:Q9JKC0

Accession:Q9JKC0

Background:CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with an chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with an aspirin-exacerbated respiratory disease.

Concentration:

Activity:Not validated for activity

Sequence:Val27-Val119

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 30.1 kDa

ObservedMW:33 kDa