Recombinant Mouse Carbonic Anhydrase 4/CA4 Protein (aa 18-277, His Tag)

SKU: PKSM040973

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: Carbonic Anhydrase 4;CA4

Target Synonym: CA-IV;CA4;CAIV;Car4;Carbonate dehydratase IV;EC4.2.1.1;RP17;carbonic anhydrase 4;carbonic anhydrase IVRP17;carbonic dehydratase IV;retinitis pigmentosa 17

Research Areas:

Conjugation:

Target Species: Mouse

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: Q64444

Accession: Q64444

Background: Carbonic anhydrase 4(CA4) is an enzyme that belongs to the alpha-carbonic anhydrase family. CA4 consists of a signal peptide (residues1-17), an ectodomain (residues18-277) and a propeptide (residues278-305), which is removed in the mature form. it is predominantly expressed in the embryo. CA4 can catalyzes the reversible reaction of CO2+H2O=HCO3-+H+, and stimulates the sodium/bicarbonate transporter activity of SLC4A4. Studies have shown that this protein have a role in inherited renal abnormalities of bicarbonate transport. Alpha-carbonic anhydrase family participate in avariety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor. They show extensive diversity in tissue is attribution and in their sub cellular localization.

Concentration:

Activity: Not validated for activity

Sequence: Glu18-Ser277

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 30.5 kDa

ObservedMW: 36 kDa