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GeneBio Systems

Recombinant ILF3 Monoclonal Antibody

Recombinant ILF3 Monoclonal Antibody

AN301758L

€349,95 EUR
€349,95 EUR
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:ILF3

Target Synonym:ILF;MMP;Mpp;DRBP;NF-AT;MPHOSPH;TCP;ILF3;CBTF;DRBF;DRBP76;MMP4;MPHOSPH4;MPP4;NF-AT-90;NF110;NF110b;NF90;NF90a;NF90b;NFAR;NFAR-1;NFAR2;TCP110;TCP80;Double stranded RNA binding protein 76;Double-stranded RNA-binding protein 76;Interleukin enhancer binding factor 3;Interleukin enhancer-binding factor 3;M phase phosphoprotein 4;M-phase phosphoprotein 4;NF AT 90;Nuclear factor associated with dsRNA;Nuclear factor of activated T cells 90 kDa;Nuclear factor of activated T-cells 90 kDa;Translational control protein 80

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;IF;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A466

UNIProt ID:Q12906

Accession:

Background:Interleukin enhancer-binding factor 3 (ILF3) is a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms. ILF3 exists main two isoforms NFAR-1 (90 kDa) and -2 (110 kDa). Upon viral infection, ILF3 accumulates in the cytoplasm and participates in the innate antiviral response.

Concentration:1 mg/mL

Immunogen:Recombinant human ILF3 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:2000-1:10000;IHC 1:100-1:500;IF 1:50;FCM 1:50-1:100

Calculated MW:95 kDa

ObservedMW:90,110 kDa

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