Recombinant Human UBE2B/HR6B Protein

SKU: PKSH033179

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: UBE2B;HR6B

Target Synonym: HR6B;RAD6 Homolog B;RAD6B;UBE2B;Ubiquitin Carrier Protein B;Ubiquitin-Conjugating Enzyme E2 B;Ubiquitin-Conjugating Enzyme E2-17 kDa;Ubiquitin-Protein Ligase B;hHR6B

Research Areas: Cell biology;Cancer;epigenetics and nuclear signal;metabolism

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: None

UNIProt ID: P63146

Accession: P63146

Background: Ubiquitin-Conjugating Enzyme E2 B (UBE2B) belongs to the ubiquitin-conjugating enzyme family. UBE2B can catalyze the covalent attachment of ubiquitin to other proteins; and is essential for the multi-ubiquitination and degradation of N-end rule substrates. UBE2B is indispensability for postreplication repair of UV-damaged DNA and may be involved in neurite outgrowth.Additionally; UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Ser152

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 10mM HEPES, pH 7.5.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 17.5 kDa

ObservedMW: 18 kDa