Recombinant Human Tetherin/BST2 Protein (His Tag)

SKU: PKSH033296

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: Tetherin;BST2

Target Synonym: BST-2;BST2;Bone Marrow Stromal Antigen 2;CD317;HM1.24 Antigen;Tetherin

Research Areas: Signal Transduction;Tags & Cell Markers;Cardiovascular;epigenetics and nuclear signal;immunology;Stem cells

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: Q10589

Accession: Q10589

Background: Bone Marrow Stromal Antigen 2 (BST2) is a single-pass type II membrane protein that belongs to the tetherin family. BST2 is predominantly expressed in the liver; lung; heart and placenta. BST2 is involved in the sorting of secreted proteins. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. BST2 is initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu; it has also been shown to inhibit the release of other viruses such as retroviruses; filoviruses; arenaviruses; and herpes viruses. BST2 may play a role in B-cell activation in rheumatoid arthritis.

Concentration:

Activity: Not validated for activity

Sequence: Asn49-Ser161

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 13.7 kDa

ObservedMW: 23 kDa