Recombinant Human PTX3 Protein(Fc Tag)

SKU: PDMH100235

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:PTX3

Target Synonym:AI607804;Pentaxin 3;Pentaxin-related protein PTX3;Pentraxin 3 long;Pentraxin-related gene;Pentraxin-related gene rapidly induced by IL-1 beta;Pentraxin-related protein PTX3;PTX3;PTX3;TNF alpha-induced protein 5;TNFAIP5;TSG-14;TSG14;Tumor necrosis factor alpha-induced protein 5;Tumor necrosis factor-inducible gene 14 protein;Tumor necrosis factor-inducible protein TSG-14

Research Areas:Cancer;Cardiovascular;Immunology

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-Fc

UNIProt ID:P26022

Accession:P26022

Background:Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells.

Concentration:

Activity:Not validated for activity

Sequence:Glu18-Ser381

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:64.9 kDa

ObservedMW:60-80 kDa