Recombinant Human IL17RB Protein(Fc Tag)

SKU: PDMH100214

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:IL17RB

Target Synonym:CRL 4;CRL4;Cytokine receptor CRL4;EVI 27;EVI27;IL 17 receptor B;IL 17 receptor homolog 1;IL 17B receptor;IL 17RB;IL 17Rh1;IL17BR;IL17RB;IL17RH1;Interleukin 17 receptor B;Interleukin 17 receptor homolog 1;Interleukin 17 receptor homolog;Interleukin 17B receptor;MGC5245

Research Areas:Immunology;Cell Biology;Cancer

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-Fc

UNIProt ID:Q9NRM6

Accession:Q9NRM6

Background:The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

Concentration:

Activity:Not validated for activity

Sequence:Arg18-Pro292

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:55.1 kDa

ObservedMW:60-80 kDa