Recombinant Human IL-29 Protein

SKU: PDMH100371

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:IL-29

Target Synonym:IFN-lambda;Interleukin;ytokine Zcyto;Cytokine Zcyto;IFNL;ZCYTO;IFN-λ;lambda;Cytokine Zcyto21;IFN-lambda-1;IFN-λ1;IL-29;interferon;interferon lambda 1;Interferon lambda-1;Interleukin-29;lambda 1;ytokine Zcyto21;IL29;ZCYTO21;IFNL1

Research Areas:Cancer;Cardiovascular;Immunology;

Conjugation:

Target Species:Human

Expression Host:HEK293 Cells

Application:

Fusion tag:N-His

UNIProt ID:Q8IU54

Accession:Q8IU54

Background:Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Concentration:

Activity:Not validated for activity

Sequence:Met1-Thr200

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% Tween 80.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:22 kDa

ObservedMW:28-35 kDa