GeneBio Systems
Recombinant Human IL-1Ra Protein
Recombinant Human IL-1Ra Protein
SKU:PDEH100726
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Size:100μg
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Exp date:12 months
Category ID_II:Recombinant Proteins
Category ID_III:Others
Abbreviation:IL-1Ra
Target Synonym:IL1F;MVCD;IL1RN;DIRA;ICIL-1RA;IL-1RN;IL-1ra;IL-1ra3;IL1F3;IL1RA;IRAP;MVCD4;Anakinra;IL1 inhibitor;Interleukin-1 receptor antagonist protein;F630041P17Rik;ICIL 1RA;ICIL1RA;IL1RN (IL1F3);Interleukin 1 receptor antagonist;Intracellular IL 1 receptor antagonist type II;Intracellular interleukin 1 receptor antagonist (icIL 1ra);MGC10430;Type II interleukin 1 receptor antagonist
Research Areas:Cancer;Cardiovascular;Immunology;
Conjugation:
Target Species:Human
Expression Host:E.coli
Application:
Fusion tag:N-His
UNIProt ID:P18510
Accession:P18510
Background:Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure.
Concentration:
Activity:Not validated for activity
Sequence:Arg26-Glu177
Purity: > 90% as determined by reducing SDS-PAGE.
Formulation:Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% Tween 80.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.
Calculated MW:19.4 kDa
ObservedMW:19 kDa
