Recombinant Human FGF basic Protein(Trx Tag)

SKU: PDEH100657

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:FGF basic

Target Synonym:HBGF;FGF;BFGF;FGF-2;FGFB;HBGF-2;Basic FGF;FGF2;Basic Fibroblast Growth Factor;B-FGF;FGF-β;Fibroblast Growth Factor 2;heparin-binding growth factor 2;prostatropin;BFGF;B-FGF;FGF-2;FGFB;fibroblast growth factor 2;HBGF-2;heparin-binding growth factor 2;prostatropin;basic;Basic fibroblast growth factor bFGF;FGF 2;FGF B;FGF2 basic;Fibroblast growth factor;Fibroblast growth factor 2 (basic);HBGF 2;HBGF2;HBGH 2;HBGH2;Heparin binding growth factor 2 precursor;heparin-binding growth factor 2;FGF-β

Research Areas:Cardiovascular;Signal Transduction;Neuroscience;Stem Cells;Cancer;Developmental Biology

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-Trx

UNIProt ID:P09038

Accession:P09038

Background:Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.

Concentration:

Activity:Not validated for activity

Sequence:Pro143-Ser288

Purity:> 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method

Calculated MW:36.1 kDa

ObservedMW:33 kDa