Recombinant Human ECF/CCL11 Protein(Sumo Tag)

SKU: PDEH100544

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:ECF/CCL11

Target Synonym:C-C motif chemokine 11;CCL 11;CCL11;CCL11;chemokine (C-C motif) ligand 11;Chemokine C C motif ligand 11;Chemokine CC Motif Ligand 11;Chemokine ligand 11;Eosinophil chemotactic protein;Eotaxin;eotaxin-1;MGC22554;SCYA 11;SCYA11;Small inducible cytokine A11;Small inducible cytokine subfamily A (Cys Cys) member 11;small inducible cytokine subfamily A (Cys-Cys);member 11 (eotaxin);Small inducible cytokine subfamily A member 11;Small-inducible cytokine A11

Research Areas:Cancer;Immunology

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-Sumo

UNIProt ID:P51671

Accession:P51671

Background:This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Concentration:

Activity:Not validated for activity

Sequence:Gly24-Pro97

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:24.1 kDa

ObservedMW:28 kDa