Recombinant Human CDO/CDON Protein (His Tag)

SKU: PKSH033720

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: CDO;CDON

Target Synonym: CDO;CDON;Cell adhesion molecule-related/down-regulated by oncogenes

Research Areas: epigenetics and nuclear signal;Stem cells

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: Q4KMG0

Accession: Q4KMG0

Background: CDO (CAMrelated/down-regulatedby oncogenes) is a member of the Immunoglubulin (Ig) superfamily, Ig/Fibronectin (FN)type III repeat family of cell surface proteins. Human CDO is a type I transmembrane (TM) glycoprotein. It is synthesized as a 1287 amino acid (aa) precursorthat contains a 25 aa signal sequence, a 938 aa extracellular domain (ECD), a 21 aa TM segment and a 303 aa cytoplasmic region. The ECD contains five C2-typeIglikedomains, followed by three FN type III repeats. The ECD of human CDO is 85% aa identical to mouse CDO ECD.CDO is found on muscle precursor and neural progenitor cells of the embryo. It likely promotes muscle differentiation, and contributes to axon guidance andneuronal patterning.

Concentration:

Activity: Not validated for activity

Sequence: Asp26-Pro943

Purity: > 85 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 100.4 kDa

ObservedMW: 120-135 kDa