Recombinant HP1α Monoclonal Antibody

SKU: AN300946L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:HP1α

Target Synonym:HEL;CBX;CBX5;HEL25;HP1;HP1A;Antigen p25;CG8409;Chromobox 5;Chromobox homolog 5;Chromobox homolog 5 (HP1 alpha homolog;Chromobox protein homolog 5;Drosophila);Epididymis luminal protein 25;Heterochromatin protein 1;Heterochromatin protein 1 alpha;Heterochromatin protein 1 homolog alpha;HP1 alpha;HP1 alpha homolog;HP1Hs alpha;Su(var)205

Research Areas:Epigenetics and Nuclear Signaling;Tags & Cell Markers

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4F3

UNIProt ID:P45973

Accession:

Background:This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human HP1α protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:400-1:2000;WB 1:1000-1:5000

Calculated MW:22 kDa

ObservedMW:22 kDa