Recombinant HIF-1 alpha/HIF1A Monoclonal Antibody

SKU: AN300409P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:HIF1A

Target Synonym:HIF;MOP;PASD;member of PAS protein;hypoxia inducible factor;bHLHe;HIF-1A;HIF1-ALPHA;HIF-1alpha;HIF1A;bHLHe78;HIF1;MOP1;PASD8;HIF-1-alpha;hypoxia inducible factor 1;alpha subunit;basic helix-loop-helix transcription factor;hypoxia-inducible factor 1-alpha;HIF 1alpha;member of PAS protein 1;ARNT interacting protein;ARNT-interacting prot;alpha subunit (basic helix loop helix transcription factor);ARNT-interacting protein;Basic helix loop helix PAS protein MOP1;Basic-helix-loop-helix-PAS protein MOP1;Class E basic helix-loop-helix protein 78;HIF 1A;HIF1 A;HIF1 Alpha;Hypoxia inducible factor 1 alpha;Hypoxia inducible factor 1 alpha isoform I.3;Hypoxia inducible factor 1 alpha subunit;Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor;Hypoxia inducible factor1alpha;Member of PAS superfamily 1;Member of the PAS Superfamily 1;MOP 1;PAS domain-containing protein 8;PASD 8

Research Areas:Cardiovascular;Epigenetics and Nuclear Signaling;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:ICC/IF

Isotype:IgG

Clonality:Monoclonal

Clone NO.:5D7

UNIProt ID:Q16665

Accession:

Background:The hypoxia-inducible transcription factor 1 alpha (HIF-1 alpha ) is the regulated member of the transcription factor heterodimer HIF-1. HIF-1 binds to hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, which illustrates the broad impact of gene regulation by HIF-1 alpha.

Concentration:1 mg/mL

Immunogen:Recombinant Human HIF-1 alpha/HIF1A Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:ICC/IF 1:20-1:100

Calculated MW:111 kDa

ObservedMW:111 kDa