Recombinant Cytochrome P450 2D6 Monoclonal Antibody

SKU: E-AB-81500

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:Cytochrome P450 2D6

Target Synonym:CPD6;CYP2D;CYP2D6;CYP2D7AP;CYP2D7BP;CYP2D7P2;CYP2D8P2;CYP2DL1;CYPIID6;Cytochrome P450 DB1;Cytochrome P450 family 2 subfamily D member 6;Cytochrome P450 family 2 subfamily D polypeptide 6;Debrisoquine 4 hydroxylase;Flavoprotein linked monooxygenase;Microsomal monooxygenase;P450 DB1;P450C2D;P450DB1;Xenobiotic monooxygenase

Research Areas:Cardiovascular;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC-P;IF

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R07-3G8

UNIProt ID:P10635

Accession:

Background:CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics,adrenoceptor antagonists,and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.

Concentration:300 μg/mL

Immunogen:Recombinant protein of human CYP2D6

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100;IF 1:50-1:100

Calculated MW:56kDa

ObservedMW:50kDa