Recombinant Cynomolgus FGL1 (C-Avi-6His) Biotinylated

SKU: PKSQ050098

Size: 100μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: FGL1

Target Synonym: FGL1;Fibrinogen-like protein 1;HFREP-1;HP-041;Hepassocin;LFIRE-1

Research Areas:

Conjugation: Biotinylated

Target Species: Cynomolgus macaques

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Avi-His

UNIProt ID: A0A2K5X990

Accession: A0A2K5X990

Background: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.

Concentration:

Activity: Not validated for activity

Sequence: Leu23-Ile312

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 34.8 kDa

ObservedMW: 36 kDa