Recombinant Cleaved N-terminal GSDMD Monoclonal Antibody

SKU: AN300650L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Cleaved N-terminal GSDMD

Target Synonym:FKSG;GSDMDC;DF5L;DFNA5L;FKSG10;GSDMDC1;GSDMD;GSDMD

Research Areas:Cell Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:8D10

UNIProt ID:P57764

Accession:

Background:GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently,GSDMD is identified as a new component of inflammasomes,and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Cleaved N-terminal GSDMD protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:53 kDa

ObservedMW:35 kDa