Recombinant ALK-1/ACVRL1 Monoclonal Antibody

SKU: AN300174P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:ACVRL1

Target Synonym:SKR;ORW;Activin Receptor-Like Kinase;Serine/Threonine-Protein Kinase Receptor R;ACVRL;ACVRLK;ALK;ACVRL1;ACVRLK1;ALK-1;ALK1;HHT;HHT2;ORW2;SKR3;TSR-I;Activin Receptor-Like Kinase 1;Serine/Threonine-Protein Kinase Receptor R3;TGF-B Superfamily Receptor Type I

Research Areas:Cardiovascular;Signal Transduction;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IP

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:7B6

UNIProt ID:P37023

Accession:

Background:This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Concentration:1 mg/mL

Immunogen:Recombinant Human ALK-1 / ACVRL1 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;IP 1-4 μL/mg of lysate

Calculated MW:56 kDa

ObservedMW:41 kDa