REC8 Antibody - Cat. #: CSB-PA939960

SKU: CSB-PA939960

Size :100ul

Clone Number:

Aliases:Cohesin Rec8p antibody; Human homolog of rad21 S. pombe antibody; Meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family antibody; Meiotic recombination protein REC8 homolog antibody; Meiotic recombination protein REC8-like 1 antibody; rec8 antibody; REC8 homolog (yeast) antibody; REC8 like 1 antibody; REC8_HUMAN antibody; Rec8p antibody; Recombination and sister chromatid cohesion protein homolog antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95072

Immunogen:Synthesized peptide derived from internal of Human REC8.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II By similarity.

Parisi S., Mol. Cell. Biol. 19:3515-3528(1999).
Ota T., Nat. Genet. 36:40-45(2004).
Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:REC8

Research Areas:Epigenetics and Nuclear Signaling;Cell biology