RCC1 Antibody - Cat. #: CSB-PA068328

SKU: CSB-PA068328

Size :100ul

Clone Number:

Aliases:Cell cycle regulatory protein antibody; CHC 1 antibody; CHC1 antibody; Chromosome condensation 1 antibody; Chromosome condensation protein 1 antibody; Guanine nucleotide releasing protein antibody; HERC2 antibody; Ran GEF antibody; RanGEF antibody; RCC 1 antibody; RCC1 antibody; RCC1 I antibody; RCC1_HUMAN antibody; Regulator of chromosome condensation 1 antibody; Regulator of chromosome condensation antibody; SHEP1 antibody; SNHG3 RCC1 antibody; SNHG3 RCC1 readthrough transcript antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P18754

Immunogen:Synthesized peptide derived from Human RCC1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

M Dasso, Mol. Cell. Biol., Aug 1992; 12: 3337 - 3345.
Hoi Yeung Li, J. Cell Biol., Mar 2003; 160: 635.
Michael E. Nemergut, Science, May 2001; 292: 1540.
Ian Cushman, Mol. Biol. Cell, Jan 2004; 15: 245.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RCC1

Research Areas:Cell biology