Rat Ryanodine Receptor 2, RYR2 ELISA Kit

SKU: E1531Ra

Size:96 Tests-1 Kit

Background:Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:RYR2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.024ng/ml

Detection range:0.05-10ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Ryanodine receptor 2

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:B0LPN4

MASS(Da):562,955

GeneID:689560

Synonyms:Cardiac muscle ryanodine receptor;Cardiac muscle ryanodine receptor-calcium release Channel;Ryanodine receptor 2;RyR;RYR2;RYR-2;Type 2 ryanodine receptor

Gene names:Ryr2

Standard solution:12.8ng/ml