Rat Neural-Cadherin,CDH2 ELISA KIT

SKU: E1189Ra

Size:96 Tests-1 Kit

Background:Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. {ECO:0000250|UniProtKB:P15116}.

Research_area:

Applications:ELISA

Target_protein:Cdh2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.12ng/ml

Detection range:0.25-16ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Neural-Cadherin

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Z1Y3

MASS(Da):99686

GeneID:83501

Synonyms:Cdh2

Gene names:Cdh2

Standard solution:32ng/ml