Rat Mothers Against Decapentaplegic Homolog 1, SMAD1 ELISA Kit

SKU: E0077Ra

Size:96 Tests-1 Kit

Background:Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). Has been shown to be also activated by TGF-beta (transforming growth factor) type I receptor kinase in rat intestinal epithelial cells (IEC 4-1). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (By similarity).

Research_area:Signal Transduction; Epigenetics and Nuclear Signaling; Cancer

Applications:ELISA

Target_protein:Smad1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:4.1ng/L

Detection range:8.12-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Mothers against decapentaplegic homolog 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P97588

MASS(Da):52,713

GeneID:25671

Synonyms:MAD homolog 1;Madh1;Mothers against decapentaplegic homolog 1;Mothers against DPP homolog 1;SMAD 1;SMAD family member 1;Smad1

Gene names:Smad1

Standard solution:2400ng/L