Rat Kynurenine 3-monooxygenase, KMO ELISA Kit

SKU: E2127Ra

Size:96 Tests-1 Kit

Background:Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.

Research_area:Others

Applications:ELISA

Target_protein:KMO

Reactivity:Rat

Assay type:Sandwich

Sensitivity:4.42ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Kynurenine 3-Monooxygenase

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O88867

MASS(Da):54,353

GeneID:59113

Synonyms:KMO;Kynurenine 3-hydroxylase;Kynurenine 3-monooxygenase

Gene names:KMO

Standard solution:2400ng/L