Rat Kappa-type opioid receptor,Oprk1 ELISA KIT

SKU: E3357Ra

Size:96 Tests-1 Kit

Background:G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions. {ECO:0000269|PubMed:20358363, ECO:0000269|PubMed:8240267}.

Research_area:

Applications:ELISA

Target_protein:Oprk1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.55ng/ml

Detection range:1.25-80ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P34975

MASS(Da):42688

GeneID:29335

Synonyms:Oprk1 Ror-d

Gene names:Oprk1

Standard solution:160ng/ml