Rat Hormone-sensitive Lipase, LIPE ELISA Kit

SKU: E1344Ra

Size:96 Tests-1 Kit

Background:Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters and retinyl esters (PubMed: 6643478, PubMed: 9162045, PubMed: 10694408). Shows a preferential hydrolysis of DAGs over TAGs and MAGs and preferentially hydrolyzes the fatty acid (FA) esters at the sn-3 position of DAGs (By similarity). Preferentially hydrolyzes fatty acids at the sn-1 and sn-2 positions of TAGs (PubMed: 6643478). Catalyzes the hydrolysis of 2-arachidonoylglycerol, an endocannabinoid and of 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (By similarity). In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production (PubMed: 1770312).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:LIPE

Reactivity:Rat

Assay type:Sandwich

Sensitivity:3.17mU/mL

Detection range:6-1800mU/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Hormone-Sensitive Lipase

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P15304

MASS(Da):116,812

GeneID:25330

Synonyms:Hormone-sensitive lipase;HSL;LIPE;Monoacylglycerol lipase LIPE;REH;Retinyl ester hydrolase

Gene names:LIPE

Standard solution:1920mU/mL