Rat Homeobox protein Nkx-2.1,NKX2-1 ELISA KIT

SKU: E1138Ra

Size:96 Tests-1 Kit

Background:Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation (By similarity). Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (PubMed:22356123). {ECO:0000250|UniProtKB:P50220, ECO:0000269|PubMed:22356123}.

Research_area:

Applications:ELISA

Target_protein:Nkx2-1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.21ng/mL

Detection range:0.38-24ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Homeobox protein Nkx-2.1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P23441

MASS(Da):38554

GeneID:

Synonyms:Nkx2-1 Nkx-2.1 Titf1 Ttf-1 Ttf1

Gene names:Nkx2-1

Standard solution:48ng/mL