Rat Fatty-acid Amidehydrolase 1, FAAH ELISA Kit

SKU: E1961Ra

Size:96 Tests-1 Kit

Background:Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules (PubMed: 9122178, PubMed: 9299394, PubMed: 9790682, PubMed: 10526230, PubMed: 11128635, PubMed: 15533037, PubMed: 17649977). Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (PubMed: 9122178, PubMed: 11128635). It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol) (PubMed: 10526230, PubMed: 15533037, PubMed: 17649977). FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids (By similarity).

Research_area:Metabolism

Applications:ELISA

Target_protein:FAAH

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.026ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Fatty-Acid Amide Hydrolase 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P97612

MASS(Da):63,357

GeneID:100911581

Synonyms:Anandamide amidase;Anandamide amidohydrolase 1;FAAH;Fatty acid ester hydrolase;Fatty-acid amide hydrolase 1;Oleamide hydrolase 1

Gene names:FAAH

Standard solution:24ng/mL