Rat chemokine,C-C motif, ligand 2,CCL2 ELISA KIT

SKU: E1293Ra

Size:96 Tests-1 Kit

Background:Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity). {ECO:0000250|UniProtKB:P10148, ECO:0000250|UniProtKB:P13500}.

Research_area:

Applications:ELISA

Target_protein:Ccl2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:1.14ng/L

Detection range:2-600ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:chemokine,C-C motif, ligand 2

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P14844

MASS(Da):16460

GeneID:24770

Synonyms:Ccl2 Je Mcp1 Scya2

Gene names:Ccl2

Standard solution:800ng/L