Rat ATP-sensitive inward rectifier potassium channel 10,KCNJ10 ELISA KIT

SKU: E1038Ra

Size:96 Tests-1 Kit

Background:May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules (By similarity). {ECO:0000250|UniProtKB:P78508}.

Research_area:

Applications:ELISA

Target_protein:Kcnj10

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.14ng/ml

Detection range:0.31-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:ATP-sensitive inward rectifier potassium channel 10

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P49655

MASS(Da):42480

GeneID:29718

Synonyms:Kcnj10 Kab-2

Gene names:Kcnj10

Standard solution:40ng/ml