Rad52(Phospho Tyr104) Polyclonal Antibody

SKU: BT-AP13514

Size:100μL

Background:The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Research_area:Epigenetics and nuclear signaling

Target_protein:RAD52

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Monkey

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DNA repair protein RAD52 homolog

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):46169

UniProt accession:Human: P43351; Mouse: P43352

Synonyms:DNA repair protein RAD52 homolog; RAD52; DNA repair protein RAD52 homolog

GeneID:Human: 5893; Mouse: 19365