PTPRN Polyclonal Antibody

SKU: E-AB-52202

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PTPRN

Target Synonym: CA 512;FLJ16131;IA 2;IA 2/PTP;IA2;IA2/PTP;ICA 3;ICA 512;ICA3;ICA512;Islet cell antigen 2;Islet cell antigen 512;Islet cell autoantigen 3;Protein tyrosine phosphatase like N;Protein tyrosine phosphatase like N precursor;Protein tyrosine phosphatase receptor type N;PTP IA 2;PTP IA-2;PTP IA2;PTPIA 2;PTPN;Ptprn;PTPRN protein;PTPRN;R PTP N;R-PTP-N;Receptor type tyrosine protein phosphatase like N;Receptor-type tyrosine-protein phosphatase-like N;RPTPN

Research Areas: Cancer;Metabolism;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q16849

Accession:

Background: IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family,which contains a transmembrane region,an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.

Concentration: 0.96 mg/mL

Immunogen: Fusion protein of human PTPRN

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: