PTPRD Monoclonal Antibody

SKU: BT-MCA2992

Size:100μL

Background:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.

Research_area:Neuroscience, Signal transduction

Target_protein:PTPRD

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5H5D7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PTPRD

Immunogen:Purified recombinant fragment of human PTPRD (AA: extra 1077-1265) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):214.8kDa

UniProt accession:P23468

Synonyms:HPTP, PTPD, HPTPD, HPTPDELTA, RPTPDELTA

GeneID:5789