PTPMT1 antibody , Cat. # FNab06931

SKU: FNab06931

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate(PGP) to phosphatidylglycerol(PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells(By similarity).

Immunogen:protein tyrosine phosphatase, mitochondrial 1

Synonyms:MOSP, PLIP

Observed MW:21-23 kDa

Uniprot ID:Q8WUK0

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:200-1:1000; IHC: 1:20-1:200

Gene ID:114971

Research Area:Metabolism