PTPA Polyclonal Antibody

SKU: E-AB-53148

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PTPA

Target Synonym:subunit B'';KIAA0044 ;MGC2184 ;Phosphotyrosyl phosphatase activator;PP2A;PP2A phosphatase activator ;PP2A subunit B';PP2A subunit B' isoform PR53;PP2A subunit B' PR53 isoform ;PPP2R4;PR53 ;PR53 isoform;Protein phosphatase 2; regulatory subunit B-prime;Protein phosphatase 2A activator regulatory subunit 4;Protein phosphatase 2A regulatory subunit B' (PR 53);PTPA;PTPA;Serine/threonine protein phosphatase 2A regulatory subunit B' ;Serine/threonine-protein phosphatase 2A activator;Serine/threonine-protein phosphatase 2A regulatory subunit 4;Serine/threonine-protein phosphatase 2A regulatory subunit B''

Research Areas:Signal transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q15257

Accession:

Background:Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration:1.08 mg/mL

Immunogen:Fusion protein of human PTPA

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: