PTH1R Monoclonal Antibody

SKU: BT-MCA3610

Size:100μL

Background:The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Research_area:Signal Transduction

Target_protein:PTH1R

applications:IHC, ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:4D2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PTH1R

Immunogen:Purified recombinant fragment of human PTH1R expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):66kDa

UniProt accession:Q03431

Synonyms:PFE, PTHR, PTHR1, MGC138426, MGC138452, PTH1R

GeneID:5745