PSMD2 Antibody - Cat. #: CSB-PA693337

SKU: CSB-PA693337

Size :50ul

Clone Number:

Aliases:26S proteasome non-ATPase regulatory subunit 2 antibody; 26S proteasome regulatory subunit RPN1 antibody; 26S proteasome regulatory subunit S2 antibody; 26S proteasome subunit p97 antibody; 55.11 protein antibody; MGC14274 antibody; P97 antibody; Proteasome (prosome macropain) 26S subunit non ATPase 2 antibody; Proteasome 26S subunit; non-ATPase; 2 antibody; Proteasome 26S; subunit 2 antibody; Protein 55.11 antibody; Psmd2 antibody; PSMD2_HUMAN antibody; Rpn1 antibody; S2 antibody; TNFR associated protein 2 antibody; TRAP2 antibody; Tumor necrosis factor receptor associated protein 2 antibody; Tumor necrosis factor type 1 receptor-associated protein 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13200

Immunogen:Fusion protein of Human PSMD2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Background:The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PSMD2

Research Areas:Cell biology