PRP8 Polyclonal Antibody

SKU: BT-AP13327

Size:100μL

Background:Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

Research_area:Epigenetics and nuclear signaling; Neuroscience

Target_protein:PRPF8

applications:IHC-p, IF

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Pre-mRNA-processing-splicing factor 8

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q6P2Q9; Mouse: Q99PV0

Synonyms:Pre-mRNA-processing-splicing factor 8 ;220 kDa U5 snRNP-specific protein;PRP8 homolog;Splicing factor Prp8;p220

GeneID:Human: 10594