PRKCQ antibody , Cat. # FNab10092

SKU: FNab10092

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.

Immunogen:PRKCQ

Synonyms:PRKCQ, PRKCT, nPKC-theta, protein kinase C theta

Observed MW:85 kDa

Uniprot ID:Q04759

Reactivity:Human

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:50 - 1:200

Gene ID:5588

Research Area:Cell Division and Proliferation, Signal Transduction, Metabolism, cancer, Immunology