Prf1 Antibody, Biotin conjugated - Cat. #: CSB-PA018668LD01MO

SKU: CSB-PA018668LD01MO

Size :50ug

Clone Number:

Aliases:Prf1 antibody; Pfp antibody; Perforin-1 antibody; P1 antibody; Cytolysin antibody; Lymphocyte pore-forming protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Mus musculus (Mouse)

UniProt ID:P10820

Immunogen:Recombinant Mouse Perforin-1 protein (21-554AA)

Raised in:Rabbit

Species Reactivity:Mouse

Tested Applications:ELISA

Background:Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Prf1

Research Areas:Immunology