PPP2R4 Monoclonal Antibody

SKU: BT-MCA3750

Size:100μL

Background:Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research_area:Signal transduction

Target_protein:PPP2R4

applications:IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:4D9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PPP2R4

Immunogen:Purified recombinant fragment of human PPP2R4 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):41kDa

UniProt accession:Q15257

Synonyms:PP2A, PR53, PTPA

GeneID:5524